Description
Myostatin HMP: A Key Player in Muscle Regulation
Myostatin HMP, also referred to as growth differentiation factor 8 (GDNF-8), is a protein encoded by the MSTN gene and holds a pivotal role in the intricate landscape of muscle development. Synthesized primarily in skeletal muscle cells, Myostatin HMP operates as a member of the TGF-beta superfamily, serving as a negative regulator of skeletal muscle mass.
In its circulating form, Myostatin exists as a latent propeptide, binding and inhibiting Myostatin activity in vitro. Within the body, Myostatin propeptide acts as a natural antagonist, countering the effects of active Myostatin. Comprising 244 amino acids with a molecular mass of 27.8 kDa, recombinant Myostatin propeptide holds promise as a potential modulator of muscle growth.
The Myostatin molecule consists of two identical subunits, each comprised of 109 amino acids. Present in an inactive state, Myostatin necessitates protease cleavage in its NH2-terminal region to become biologically active.
Myostatin HMP Chemical Profile:
- Formula: C121H200N42O39
- Molecular Weight: 2888.16
- Chain: Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys